Mercedes-Benz S-Class trim comparison

2025 Mercedes-Benz S-Class S 500 4MATIC vs S 580e 4MATIC

The S-Class S 500 4MATIC starts at $117,750 while the S 580e 4MATIC is $128,200. That $10,450 gap buys 7 meaningful differences.

The short answer

This trim jump changes the engine from 3.0L I6 mild-hybrid to 3.0L I6 phev Turbo. Everything else is secondary to whether that powertrain difference matters for how you drive.

If you would notice the 3.0L I6 phev Turbo every week, the S 580e 4MATIC makes sense. If not, the S 500 4MATIC is the cleaner stop because this jump matters for the powertrain first and the trim badge second.

If you are budgeting this move monthly, the jump from the S 500 4MATIC to the S 580e 4MATIC is about $184/month on a 60-month loan at 6.5% APR with 10% down. That works out to roughly $11,040 more by the time interest is counted. If that different powertrain is not part of your real use case, the cheaper trim keeps more money in your pocket without changing the core experience you need.

$10,450
Price Gap
+61 HP
HP Diff
+1 MPG
MPG Diff
Trim navigation

Lock one trim, change the other side, and move through exact pair pages without resetting back to the full lineup every time.

Compare another trim against S 500 4MATIC S 500 4MATIC stays locked on this side. Use this row to test the next trim up or down while keeping the exact pair page intact.
Lower-price trim
Starts at $117,750
VS
Higher-price trim
Starts at $128,200
Base / Value: S 500 4MATIC
Clear Upgrade: S 580e 4MATIC

Who notices the difference

The higher trim starts to make more sense when you are specifically shopping for the stronger powertrain, not just more trim content.

When both feel the same

The S 500 4MATIC and S 580e 4MATIC are mechanically identical where it counts: the same 9-speed shiftable automatic transmission and identical wheelbase and body dimensions.

The upgrade math

You are paying $10,450 for 6 measurable differences, which works out to about $1,742 per change.

Key Differences at a Glance

This is the fast read: price, power, efficiency, and the feature flips most likely to change the answer.

MSRP
$117,750
vs
$128,200
Engine
3.0L I6 mild-hybrid
vs
3.0L I6 phev Turbo
Horsepower
442 hp
vs
503 hp
Fuel Economy
24 MPG combined
vs
23 MPG combined
All-weather floor mats for the 2025 Mercedes-Benz S-Class Check prices on Amazon (paid link)

Every Difference, Side by Side

This is the full read behind the quick decision signals above: the complete hardware, comfort, and equipment story. 7 specification differences, 1 shared.

Engine Biggest
S 500 4MATIC3.0L I6 mild-hybrid
S 580e 4MATIC3.0L I6 phev Turbo
Fuel Economy
S 500 4MATIC24 MPG combined
S 580e 4MATIC23 MPG combined
Curb Weight
S 500 4MATIC4,740 lbs
S 580e 4MATIC5,501 lbs
Fuel Tank
S 500 4MATIC20.0 gal

Full Specification Comparison

Specifications reflect available data as of early 2025. Confirm details with an authorized dealer before purchasing.

Spec S 500 4MATIC S 580e 4MATIC
Pricing
MSRP$117,750$128,200
Powertrain
Engine3.0L I6 mild-hybrid3.0L I6 phev Turbo
Horsepower442 hp503 hp
Torque413 lb-ft553 lb-ft
Transmission9-speed shiftable automatic9-speed shiftable automatic
DrivetrainAWDAWD
Fuel Economy
City MPG2120
Highway MPG3129
Combined MPG2423
Fuel Tank20.0 gal17.7 gal
Dimensions
Curb Weight4,740 lbs5,501 lbs
Wheelbase126.6"126.6"
Length208.2"208.2"
Width76.9"76.9"
Height59.2"59.2"
Warranty
Bumper-to-Bumper4yr/50k4yr/50k
Powertrain4yr/50k4yr/50k
Corrosion4yr/50k4yr/50k
Roadside Assistance4yr/50k4yr/50k

Data sources: licensed third-party automotive data, EPA fueleconomy.gov, NHTSA, and official manufacturer materials. Values marked est. are estimated.

2025 Mercedes-Benz S-Class S 500 4MATIC vs S 580e 4MATIC Questions Shoppers Ask

Use this page for the direct trim answer, then zoom back out to the Mercedes-Benz S-Class lineup, the Mercedes-Benz brand hub, the Full-Size Sedans, the how to pick a trim guide, or our mid-trim value research when you need the bigger shopping path behind this one matchup.

How much more does the 2025 S-Class S 580e 4MATIC cost than the S 500 4MATIC?

The S 580e 4MATIC starts at $128,200 compared to $117,750 for the S 500 4MATIC. That is a $10,450 difference, or approximately $184/month more on a 60-month loan.

Do the 2025 Mercedes-Benz S-Class S 500 4MATIC and S 580e 4MATIC have the same engine?

No. The S 500 4MATIC uses a 3.0L I6 mild-hybrid (442 hp, 413 lb-ft), while the S 580e 4MATIC has the 3.0L I6 phev Turbo (503 hp, 553 lb-ft). That is 61 more horsepower. Both pair with the same 9-speed shiftable automatic.

Do the 2025 S-Class S 500 4MATIC and S 580e 4MATIC have the same drivetrain?

Yes. Both come with AWD as standard. The differences between these trims are in features and equipment, not drivetrain.

What warranty does the 2025 Mercedes-Benz S-Class come with?

All 2025 Mercedes-Benz S-Class trims, including both the S 500 4MATIC and S 580e 4MATIC, come with Mercedes-Benz's standard warranty: 4yr/50k bumper-to-bumper and 4yr/50k powertrain coverage. Warranty does not vary by trim level.

Is the 2025 Mercedes-Benz S-Class S 580e 4MATIC worth $10,450 more than the S 500 4MATIC?

The $10,450 buys the 3.0L I6 phev Turbo. If that powertrain matters for how you drive, yes. If not, the S 500 4MATIC does the same job for less.

Which 2025 Mercedes-Benz S-Class trim gets better fuel economy, the S 500 4MATIC or the S 580e 4MATIC?

The S 500 4MATIC is the more efficient of the two at 24 combined MPG, versus 23 for the other trim. That matters most if you are balancing running costs against the extra power, drivetrain, or comfort equipment tied to the pricier trim.

What $10,450 Gets You

The S-Class S 580e 4MATIC is a clear upgrade over the S 500 4MATIC. The $10,450 price increase gets you the 3.0L I6 phev Turbo engine (+61 hp) -- real functional changes, not just cosmetics.

S 500 4MATIC vs. S 580e 4MATIC: Day-to-Day

The S 580e 4MATIC comes with the 3.0L I6 phev Turbo instead of the S 500 4MATIC's 3.0L I6 mild-hybrid. That means 61 more horsepower and 140 more lb-ft of torque. You will notice it most when merging, passing, or climbing at speed. In return, expect about 1 fewer combined MPG.

Fuel Economy Comparison

The S-Class S 500 4MATIC gets 1 more combined MPG. At $3.50/gallon and 12,000 miles/year, that saves roughly $76 per year or $380 over five years of ownership.

Summary

The S-Class S 580e 4MATIC costs $10,450 more than the S 500 4MATIC (about $184/month more on a 60-month loan). That buys 6 meaningful changes at $1,742 per change. Whether that trade-off is worth it depends on which features matter to your daily driving.

Trim-Matched Accessories

These add-ons are split by trim intent so the recommendations follow the actual use case, not just the same repeated product block.

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Specifications shown combine licensed third-party automotive data with official manufacturer, EPA, and NHTSA source material for the 2025 model year. Actual pricing, features, and availability may vary by region and dealer. Always confirm details with an authorized dealer before making a purchase decision. TrimAtlas is not affiliated with Mercedes-Benz or any dealership.

Page updated 2026-03-18. Verify equipment, pricing, and regional availability with the manufacturer or dealer.

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