Mercedes-Benz S-Class trim comparison

2025 Mercedes-Benz S-Class S 500 4MATIC vs S 580 4MATIC

The S-Class S 500 4MATIC starts at $117,750 while the S 580 4MATIC is $128,600. That $10,850 gap buys 6 meaningful differences.

The short answer

This trim jump changes the engine from 3.0L I6 mild-hybrid to 4.0L V8 mild-hybrid Turbo. Everything else is secondary to whether that powertrain difference matters for how you drive.

If you would notice the 4.0L V8 mild-hybrid Turbo every week, the S 580 4MATIC makes sense. If not, the S 500 4MATIC is the cleaner stop because this jump matters for the powertrain first and the trim badge second.

Think about this as a monthly tradeoff, not just a sticker gap. The S 580 4MATIC adds about $191/month on a typical 60-month loan, or around $11,460 more overall with interest. If that different powertrain is not part of your real use case, the cheaper trim keeps more money in your pocket without changing the core experience you need.

$10,850
Price Gap
+54 HP
HP Diff
+4 MPG
MPG Diff
Trim navigation

Lock one trim, change the other side, and move through exact pair pages without resetting back to the full lineup every time.

Compare another trim against S 580 4MATIC S 580 4MATIC stays locked on this side. Pick a different trim for the other slot without leaving the exact head-to-head route.
S 500 4MATIC S 580e 4MATIC
Compare another trim against S 500 4MATIC S 500 4MATIC stays locked on this side. Use this row to test the next trim up or down while keeping the exact pair page intact.
Lower-price trim
Starts at $117,750
VS
Higher-price trim
Starts at $128,600
Base / Value: S 500 4MATIC
Clear Upgrade: S 580 4MATIC

Who notices the difference

The higher trim starts to make more sense when you are specifically shopping for the stronger powertrain, not just more trim content.

When both feel the same

The S 500 4MATIC and S 580 4MATIC are mechanically identical where it counts: the same 9-speed shiftable automatic transmission and identical wheelbase and body dimensions.

The upgrade math

You are paying $10,850 for 5 measurable differences, which works out to about $2,170 per change.

Key Differences at a Glance

This is the fast read: price, power, efficiency, and the feature flips most likely to change the answer.

MSRP
$117,750
vs
$128,600
Engine
3.0L I6 mild-hybrid
vs
4.0L V8 mild-hybrid Turbo
Horsepower
442 hp
vs
496 hp
Fuel Economy
24 MPG combined
vs
20 MPG combined
All-weather floor mats for the 2025 Mercedes-Benz S-Class Check prices on Amazon (paid link)

Every Difference, Side by Side

This is the full read behind the quick decision signals above: the complete hardware, comfort, and equipment story. 6 specification differences, 1 shared.

Engine Biggest
S 500 4MATIC3.0L I6 mild-hybrid
S 580 4MATIC4.0L V8 mild-hybrid Turbo
Fuel Economy
S 500 4MATIC24 MPG combined
S 580 4MATIC20 MPG combined
Curb Weight
S 500 4MATIC4,740 lbs
S 580 4MATIC4,784 lbs

Full Specification Comparison

Specifications reflect available data as of early 2025. Confirm details with an authorized dealer before purchasing.

Spec S 500 4MATIC S 580 4MATIC
Pricing
MSRP$117,750$128,600
Powertrain
Engine3.0L I6 mild-hybrid4.0L V8 mild-hybrid Turbo
Horsepower442 hp496 hp
Torque413 lb-ft516 lb-ft
Transmission9-speed shiftable automatic9-speed shiftable automatic
DrivetrainAWDAWD
Fuel Economy
City MPG2117
Highway MPG3125
Combined MPG2420
Fuel Tank20.0 gal20.0 gal
Dimensions
Curb Weight4,740 lbs4,784 lbs
Wheelbase126.6"126.6"
Length208.2"208.2"
Width76.9"76.9"
Height59.2"59.2"
Warranty
Bumper-to-Bumper4yr/50k4yr/50k
Powertrain4yr/50k4yr/50k
Corrosion4yr/50k4yr/50k
Roadside Assistance4yr/50k4yr/50k

Data sources: licensed third-party automotive data, EPA fueleconomy.gov, NHTSA, and official manufacturer materials. Values marked est. are estimated.

2025 Mercedes-Benz S-Class S 500 4MATIC vs S 580 4MATIC Questions Shoppers Ask

Use this page for the direct trim answer, then zoom back out to the Mercedes-Benz S-Class lineup, the Mercedes-Benz brand hub, the Full-Size Sedans, the how to pick a trim guide, or our mid-trim value research when you need the bigger shopping path behind this one matchup.

How much more does the 2025 S-Class S 580 4MATIC cost than the S 500 4MATIC?

The S 580 4MATIC starts at $128,600 compared to $117,750 for the S 500 4MATIC. That is a $10,850 difference, or approximately $191/month more on a 60-month loan.

Do the 2025 Mercedes-Benz S-Class S 500 4MATIC and S 580 4MATIC have the same engine?

No. The S 500 4MATIC uses a 3.0L I6 mild-hybrid (442 hp, 413 lb-ft), while the S 580 4MATIC has the 4.0L V8 mild-hybrid Turbo (496 hp, 516 lb-ft). That is 54 more horsepower. Both pair with the same 9-speed shiftable automatic.

Do the 2025 S-Class S 500 4MATIC and S 580 4MATIC have the same drivetrain?

Yes. Both come with AWD as standard. The differences between these trims are in features and equipment, not drivetrain.

What warranty does the 2025 Mercedes-Benz S-Class come with?

All 2025 Mercedes-Benz S-Class trims, including both the S 500 4MATIC and S 580 4MATIC, come with Mercedes-Benz's standard warranty: 4yr/50k bumper-to-bumper and 4yr/50k powertrain coverage. Warranty does not vary by trim level.

Is the 2025 Mercedes-Benz S-Class S 580 4MATIC worth $10,850 more than the S 500 4MATIC?

The $10,850 buys the 4.0L V8 mild-hybrid Turbo. If that powertrain matters for how you drive, yes. If not, the S 500 4MATIC does the same job for less.

Which 2025 Mercedes-Benz S-Class trim gets better fuel economy, the S 500 4MATIC or the S 580 4MATIC?

The S 500 4MATIC is the more efficient of the two at 24 combined MPG, versus 20 for the other trim. That matters most if you are balancing running costs against the extra power, drivetrain, or comfort equipment tied to the pricier trim.

Breaking Down the $10,850 Gap

The S 580 4MATIC earns its premium. For $10,850 more, you get the 4.0L V8 mild-hybrid Turbo engine (+54 hp), making this one of the more straightforward upgrade decisions in the S-Class lineup.

How the S 500 4MATIC and S 580 4MATIC Feel Different

Moving from the S 500 4MATIC to the S 580 4MATIC means a different engine entirely. That means 54 more horsepower and 103 more lb-ft of torque. You will notice it most when merging, passing, or climbing at speed. In return, expect about 4 fewer combined MPG.

Fuel Economy Comparison

The S-Class S 500 4MATIC gets 4 more combined MPG. At $3.50/gallon and 12,000 miles/year, that saves roughly $350 per year or $1,750 over five years of ownership.

The Short Version

The S-Class S 580 4MATIC costs $10,850 more than the S 500 4MATIC (about $191/month more on a 60-month loan). That buys 5 meaningful changes at $2,170 per change. Whether that trade-off is worth it depends on which features matter to your daily driving.

Trim-Matched Accessories

These add-ons are split by trim intent so the recommendations follow the actual use case, not just the same repeated product block.

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Specifications shown combine licensed third-party automotive data with official manufacturer, EPA, and NHTSA source material for the 2025 model year. Actual pricing, features, and availability may vary by region and dealer. Always confirm details with an authorized dealer before making a purchase decision. TrimAtlas is not affiliated with Mercedes-Benz or any dealership.

Page updated 2026-03-18. Verify equipment, pricing, and regional availability with the manufacturer or dealer.

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