2025 Audi A4 Premium Plus S line vs 2025 Lexus ES 350

On paper, the 2025 Lexus ES 350 wins on $6,460 less, 41 more hp, 8.4″ longer. The 2025 Audi A4 Premium Plus S line has to win you at the dealer. Key numbers: 261 vs 302 hp, 26 vs 25 MPG.

The short answer

The A4 Premium Plus S line leads on AWD. The ES 350 leads on $6,460 less, 41 more hp. The spec table compares 7 specifications head to head.

N/A
Price Gap
41 HP
HP Diff
1 MPG
Efficiency Diff
Vehicle A
2025 Audi A4 Premium Plus S line
Starts at $48,600
VS
Vehicle B
2025 Lexus ES 350
Starts at $42,140

Key Differences at a Glance

Engine
2.0L I4 mild-hybrid Turbo
vs
3.5L V6
Horsepower
261 hp
vs
302 hp
Torque
273 lb-ft
vs
267 lb-ft
Drivetrain
AWD
vs
FWD
Fuel Economy
26 MPG combined
vs
25 MPG combined

What's Actually Different

These two vehicles differ in 7 specifications.

MSRP
$48,600A4 Premium Plus S line
$42,140ES 350
Engine
2.0L I4 mild-hybrid TurboA4 Premium Plus S line
3.5L V6ES 350
Horsepower
261 hpA4 Premium Plus S line
302 hpES 350
Torque
273 lb-ftA4 Premium Plus S line
267 lb-ftES 350
Transmission
7-speed automated manualA4 Premium Plus S line
8-speed shiftable automaticES 350
Drivetrain
AWDA4 Premium Plus S line
FWDES 350
City MPG
23A4 Premium Plus S line
22ES 350
Combined MPG
26A4 Premium Plus S line
25ES 350
Fuel Tank
15.3 galA4 Premium Plus S line
15.9 galES 350
Curb Weight
3,682 lbsA4 Premium Plus S line
3,690 lbsES 350
Wheelbase
111.0"A4 Premium Plus S line
113.0"ES 350
Length
187.5"A4 Premium Plus S line
195.9"ES 350
Width
72.7"A4 Premium Plus S line
73.4"ES 350
Height
56.2"A4 Premium Plus S line
56.9"ES 350
Powertrain
4yr/50kA4 Premium Plus S line
6yr/70kES 350
Corrosion
12yr/unlimitedA4 Premium Plus S line
6yr/unlimitedES 350

Full Specification Comparison

Specifications and pricing reflect available data as of early 2026 and may not match current manufacturer figures. Always confirm details with an authorized dealer before making a purchase decision.

Spec2025 Audi A4 Premium Plus S line2025 Lexus ES 350
Pricing
MSRP$48,600$42,140
Powertrain
Engine2.0L I4 mild-hybrid Turbo3.5L V6
Horsepower261 hp302 hp
Torque273 lb-ft267 lb-ft
Transmission7-speed automated manual8-speed shiftable automatic
DrivetrainAWDFWD
Fuel Economy
City MPG2322
Highway MPG3232
Combined MPG2625
Fuel Tank15.3 gal15.9 gal
Annual Fuel Cost (EPA)No published data$1,750/yr
Dimensions
Curb Weight3,682 lbs3,690 lbs
Wheelbase111.0"113.0"
Length187.5"195.9"
Width72.7"73.4"
Height56.2"56.9"
Safety
NHTSA Overall5/5 stars5/5 stars
Warranty
Bumper-to-Bumper4yr/50k4yr/50k
Powertrain4yr/50k6yr/70k
Corrosion12yr/unlimited6yr/unlimited
Roadside Assistance4yr/unlimited4yr/unlimited

Frequently Asked Questions

What is the price difference between the 2025 Audi A4 Premium Plus S line and 2025 Lexus ES 350?

The 2025 Lexus ES 350 starts at $42,140, $6,460 less than the 2025 Audi A4 Premium Plus S line at $48,600. On a 60-month loan that is roughly $114/month. All prices are MSRP before destination and dealer fees.

Who should choose the 2025 Audi A4 Premium Plus S line?

The 2025 Audi A4 Premium Plus S line is the stronger pick when lower running costs matter to you, roughly $65/year less on fuel; you drive in snow, rain, or unpaved roads where AWD keeps you planted.

Who should choose the 2025 Lexus ES 350?

The 2025 Lexus ES 350 is the stronger pick when you want to keep $6,460 in your pocket and the 2025 Lexus ES 350 covers your needs; the extra 41 hp matters for your commute or driving style.

Which gets better fuel economy, the 2025 Audi A4 Premium Plus S line or 2025 Lexus ES 350?

The 2025 Audi A4 Premium Plus S line rates 26 combined MPG, 1 MPG ahead.

Which is more powerful, the 2025 Audi A4 Premium Plus S line or 2025 Lexus ES 350?

The 2025 Lexus ES 350 produces 302 hp, 41 more than the 2025 Audi A4 Premium Plus S line at 261 hp. The 2025 Audi A4 Premium Plus S line also leads in torque at 273 lb-ft vs 267 lb-ft. The 2025 Audi A4 Premium Plus S line runs a 2.0L I4 mild-hybrid Turbo; the 2025 Lexus ES 350 uses a 3.5L V6. Drivetrains differ too: AWD on the 2025 Audi A4 Premium Plus S line, FWD on the 2025 Lexus ES 350.

Is the 2025 Audi A4 Premium Plus S line bigger than the 2025 Lexus ES 350?

The 2025 Lexus ES 350 is 8.4″ longer at 195.9″ vs 187.5″. The 2025 Lexus ES 350 has a 2.0″ longer wheelbase, which typically means more rear-seat legroom.

Do the 2025 Audi A4 Premium Plus S line and 2025 Lexus ES 350 have the same drivetrain?

No. The 2025 Audi A4 Premium Plus S line comes with AWD, while the 2025 Lexus ES 350 uses FWD. If you drive in snow, heavy rain, or on unpaved roads, the all-wheel or four-wheel drive option provides better traction. If you mostly drive on dry pavement, the two-wheel drive option saves fuel.

How do the warranties compare?

The Audi A4 comes with 4yr/50k bumper-to-bumper and 4yr/50k powertrain. The Lexus ES offers 4yr/50k bumper-to-bumper and 6yr/70k powertrain. Longer warranty coverage can offset higher maintenance costs over time.

Explore more: Audi trims, Audi A4 trims, Lexus trims, Lexus ES trims

Official sources

The A4–ES Decision

Shopping compact cars means the A4 and ES will likely end up on the same test-drive day. Here is what the numbers say before you get behind the wheel. The $-6,460 gap adds up to $114/month on a 60-month loan. That is real money, so the pricier option needs to earn it with capabilities you will actually use.

What Powers Each Vehicle

The 2025 Audi A4 Premium Plus S line runs a 2.0L I4 mild-hybrid Turbo; the 2025 Lexus ES 350 uses a 3.5L V6. The 2025 Lexus ES 350 has 41 more hp (302 vs 261), enough to notice on highway on-ramps and when passing. The 2025 Audi A4 Premium Plus S line comes with AWD; the 2025 Lexus ES 350 uses FWD. If you deal with snow, rain, or gravel roads, that traction advantage matters.

The Ownership Math

The 2025 Audi A4 Premium Plus S line saves roughly $65/year on fuel at $3.50/gallon and 12,000 annual miles. Over five years, that is $325.

The Decision

Choose the 2025 Audi A4 Premium Plus S line when lower running costs matter to you, roughly $65/year less on fuel. Choose the 2025 Lexus ES 350 when you want to keep $6,460 in your pocket and the 2025 Lexus ES 350 covers your needs.

Specifications shown combine licensed third-party automotive data with official manufacturer, EPA, and NHTSA source material. Actual pricing, features, and availability may vary by region and dealer. Always confirm details with an authorized dealer before making a purchase decision. TrimAtlas is not affiliated with Audi or Lexus or any dealership.

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